SCHEMBL9575983

SCHEMBL9575983

CCCCCCCCCCCCCCCCCCNC(=O)OCC(CO)OC

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.57
ACHE P22303 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10910045 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL10899266 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL10900276 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL9693941 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL10906661 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL10910652 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL9863527 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL9575985 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL9694130 1.00 EPHX1 (0.57) EPHX1ACHE
SCHEMBL9863810 0.90 EPHX1 (0.56) EPHX1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5187293-A Blood platelet activating factor inhibitors HOFFMANN-LA ROCHE INC. (US) 1993-02-16 US disclosed
EP-0157609-B1 LIPID DERIVATIVES THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1992-10-14 EP disclosed
US-5025005-A Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US disclosed
US-4868319-A Process for the preparation of monoalkylcarbamate group-containing compounds SANDOZ PHARM. CORP. (US) 1989-09-19 US disclosed
US-4845219-A ANTITUMOR, ANTOCOAGULANT TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-07-04 US disclosed
EP-0225129-B1 PHOSPHOLIPID DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1989-05-24 EP disclosed
EP-0147768-B1 GLYCERIN DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1989-02-08 EP disclosed
US-4778912-A ANTITUMOR AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-10-18 US disclosed
US-4737518-A ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1988-04-12 US disclosed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US disclosed
EP-0255366-A2 Nitrogen- and sulfur-containing lipid compound, their production and use Takeda Chemical Industries, Ltd. (JP) 1988-02-03 EP disclosed
EP-0225129-A1 Phospholipid derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-06-10 EP disclosed
US-4582824-A TREATMENT OF VARIOUS CIRCULATORY AND ALLERGIC DISEASES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-04-15 US disclosed
US-4565865-A ANTITUMOR AGENTS, MICROBIOCIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-01-21 US disclosed
EP-0157609-A2 Lipid derivatives their production and use Takeda Chemical Industries, Ltd. (JP) 1985-10-09 EP disclosed
EP-0147768-A2 Glycerin derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-07-10 EP disclosed
US-4408052-A FUNGICIDES AND ANTITUMOR AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1983-10-04 US disclosed
EP-0035375-B1 CARBAMIC ACID ESTERS, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1983-08-10 EP disclosed
EP-0035375-A1 Carbamic acid esters, their production and use Takeda Chemical Industries, Ltd. (JP) 1981-09-09 EP disclosed