Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 11/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576272 | 1.00 | HCAR2 (0.52) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9576273 | 0.92 | HCAR2 (0.39) | HCAR2TSHRGABRA1GABRG2GABRB3 | |
| SCHEMBL10493959 | 0.89 | HCAR2 (0.46) | HCAR2 | |
| SCHEMBL9709339 | 0.83 | HCAR2 (0.53) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL9709350 | 0.83 | HCAR2 (0.53) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL28140358 | 0.83 | HCAR2 (0.53) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL10457585 | 0.83 | HCAR2 (0.49) | HCAR2TSHRMAPTATM | |
| SCHEMBL10457586 | 0.83 | HCAR2 (0.49) | HCAR2TSHRMAPTATM | |
| SCHEMBL10457671 | 0.81 | HCAR2 (0.47) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL10457668 | 0.81 | HCAR2 (0.47) | HCAR2TSHRTP53EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219884-B1 | HARD CONTACT LENS MATERIAL | Tomei Sangyo Kabushiki Kaisha (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |