Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577467 | 1.00 | CYP2C19 (0.46) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL667322 | 0.86 | CYP2C19 (0.62) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL10886683 | 0.84 | CYP2C19 (0.47) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL10886677 | 0.84 | CYP2C19 (0.47) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL10886147 | 0.81 | CYP2C19 (0.45) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL10886154 | 0.81 | CYP2C19 (0.45) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL11856879 | 0.80 | CYP2C19 (0.44) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL11856866 | 0.80 | CYP2C19 (0.44) | CYP2C19EPHX1LMNAHSD17B10UBE2N | |
| SCHEMBL9577409 | 0.79 | CYP2C19 (0.46) | CYP2C19EPHX1LMNAHSD17B10CES2 | |
| SCHEMBL9577255 | 0.79 | CYP2C19 (0.73) | CYP2C19EPHX1LMNAHSD17B10CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |