SCHEMBL9577615

SCHEMBL9577615

OC(C1=CCCCC1)C1CCCC1

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.50
IDO1 P14902 13/20 0.35
TDO2 P48775 12/20 0.35
HSD11B1 P28845 1/20 0.33
NPC1 O15118 1/20 0.33
EPHX1 P07099 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
DHODH Q02127 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13433662 0.98 HIF1A (0.53) HIF1AIDO1TDO2HSD11B1NPC1
SCHEMBL12186336 0.79 HIF1A (0.34) HIF1A
SCHEMBL11069075 0.78 HIF1A (0.40) HIF1AHSD11B1NPC1EPHX1RAB9A
SCHEMBL5706630 0.73
SCHEMBL9791343 0.73 HIF1A (0.41) HIF1AHSD11B1NPC1EPHX1RAB9A
SCHEMBL19743510 0.72 HIF1A (0.35) HIF1A
SCHEMBL19743512 0.72 HIF1A (0.35) HIF1A
SCHEMBL19743513 0.72 HIF1A (0.35) HIF1A
SCHEMBL11523172 0.72 MAPK14 (0.37) HIF1AIDO1
SCHEMBL9028549 0.72 MAPK14 (0.37) HIF1AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5240907-A Augment or enhance aroma of perfumes, colognes, perfumed articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1993-08-31 US disclosed
US-5240907-A Augment or enhance aroma of perfumes, colognes, perfumed articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1993-08-31 US disclosed
US-5240907-A Augment or enhance aroma of perfumes, colognes, perfumed articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1993-08-31 US disclosed
US-5087707-A Substituted cyclopentenyl-oxabicyclooctanes, cyclopentenyl-formylcyclohexenes and cyclopentenyl-hydroxymethyl cyclohexenes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1992-02-11 US disclosed
US-5081262-A Substituted cyclopentenyl oxabicyclooctanes, cyclopentenylformylcyclohexenes and cyclopentenylhydroxymethyl cyclohexenes, processes for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1992-01-14 US disclosed
US-5070073-A PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1991-12-03 US disclosed