⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665335 | 0.75 | — | — | |
| SCHEMBL127505 | 0.72 | SLC6A2 (0.31) | — | |
| SCHEMBL16550484 | 0.71 | — | — | |
| SCHEMBL12851469 | 0.71 | CYP3A4 (0.32) | — | |
| SCHEMBL17449732 | 0.71 | CYP3A4 (0.32) | — | |
| SCHEMBL5137869 | 0.71 | CYP3A4 (0.32) | — | |
| SCHEMBL436289 | 0.69 | — | — | |
| SCHEMBL6014609 | 0.69 | — | — | |
| SCHEMBL9678445 | 0.69 | — | — | |
| SCHEMBL10788430 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350880-B1 | HERBICIDAL COMPOSITION AND HERBICIDAL METHOD | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-04-07 | — | — | EP | claimed |
| US-9968686-B2 | Antisense oligonucleotides with improved pharmacokinetic properties | UNIVERSITY OF VIENNA (AT) | 2018-05-15 | — | — | US | disclosed |
| EP-3043823-A1 | ANTISENSE OLIGONUCLEOTIDES WITH IMPROVED PHARMACOKINETIC PROPERTIES | University of Vienna (AT) | 2016-07-20 | — | — | EP | disclosed |
| US-20160193354-A1 | ANTISENSE OLIGONUCLEOTIDES WITH IMPROVED PHARMACOKINETIC PROPERTIES | UNIVERSITY OF VIENNA (AT) | 2016-07-07 | — | — | US | disclosed |
| WO-2015032968-A1 | ANTISENSE OLIGONUCLEOTIDES WITH IMPROVED PHARMACOKINETIC PROPERTIES | UNIVERSITY OF VIENNA (AT) | 2015-03-12 | — | — | WO | disclosed |
| EP-2845607-A1 | Antisense oligonucleotides with improved pharmacokinetic properties | University of Vienna (AT) | 2015-03-11 | — | — | EP | disclosed |
| CN-1107145-A | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| CN-1078968-A | 2-Piperazinone compounds and their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-01 | — | — | CN | disclosed |
| CN-1069730-A | 2-Piperazinone compounds and their preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-03-10 | — | — | CN | disclosed |