Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257832 | 0.85 | HDAC1 (0.44) | GAAMEN1KMT2APPARGTSHR | |
| SCHEMBL9256976 | 0.80 | HDAC1 (0.46) | GAAMEN1KMT2APPARGTSHR | |
| SCHEMBL9252884 | 0.78 | HDAC1 (0.46) | GAAMAPTTP53PPARGTSHR | |
| SCHEMBL9260748 | 0.78 | PPARG (0.39) | GAAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9260818 | 0.76 | SOAT1 (0.43) | GAAMEN1KMT2APPARGNPSR1 | |
| SCHEMBL9257144 | 0.74 | HDAC6 (0.38) | GAAHTTMAPK1 | |
| SCHEMBL9257679 | 0.73 | HDAC6 (0.55) | KMT2ATSHR | |
| SCHEMBL9252264 | 0.73 | SOAT1 (0.46) | GAAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9252619 | 0.72 | HDAC1 (0.51) | GAAMAPTPPARGALDH1A1TSHR | |
| SCHEMBL9260018 | 0.70 | HDAC6 (0.47) | MEN1KMT2ASMN1; SMN2PPARGPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550568-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006075-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |