Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252064 | 0.87 | SOAT1 (0.42) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9256182 | 0.85 | SOAT1 (0.43) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9252442 | 0.85 | SOAT1 (0.45) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9256781 | 0.85 | HDAC1 (0.50) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9252305 | 0.82 | SOAT1 (0.47) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL8768964 | 0.82 | PPARA (0.46) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9259222 | 0.82 | SOAT1 (0.47) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9252062 | 0.81 | SOAT1 (0.48) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9253920 | 0.81 | HDAC1 (0.52) | SOAT1LPAR1LPAR5HDAC1HDAC6 | |
| SCHEMBL9257517 | 0.79 | HDAC1 (0.55) | SOAT1LPAR1LPAR5HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550568-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006075-A1 | ANTI-ATHEROSCLEROTIC ARYL COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |