Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.80 |
| ▸ | TP53 | P04637 | 1/20 | 0.80 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.75 |
| ▸ | BAD | Q92934 | 1/20 | 0.75 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.67 |
| ▸ | RXRA | P19793 | 4/20 | 0.65 |
| ▸ | RXRB | P28702 | 4/20 | 0.65 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.63 |
| ▸ | CA9 | Q16790 | 2/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.63 |
| ▸ | CA3 | P07451 | 1/20 | 0.63 |
| ▸ | TYR | P14679 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | CA6 | P23280 | 1/20 | 0.63 |
| ▸ | CA5A | P35218 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637326 | 1.00 | TSHR (0.80) | TSHRTP53BCL2L1BADSRD5A2 | |
| SCHEMBL14018385 | 1.00 | TSHR (0.80) | TSHRTP53BCL2L1BADSRD5A2 | |
| SCHEMBL69873 | 1.00 | TSHR (0.80) | TSHRTP53BCL2L1BADSRD5A2 | |
| SCHEMBL5998504 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 | |
| SCHEMBL21808797 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 | |
| SCHEMBL19307796 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 | |
| Water SCHEMBL22788424 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 | |
| Fluoride SCHEMBL20513068 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 | |
| Water SCHEMBL8605516 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 | |
| Hydrochloric Acid SCHEMBL894005 | 0.97 | TSHR (0.75) | TSHRTP53BCL2L1BADSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2067314-A | — | — | None | — | — | JP | disclosed |
| EP-0292251-B1 | Aromatic polyester composition and process for producing the same | TORAY INDUSTRIES (JP) | 1993-11-24 | — | — | EP | disclosed |
| JP-H0267314-A | AROMATIC POLYESTER | SEKISUI CHEM CO LTD | 1990-03-07 | — | — | JP | disclosed |
| US-4879328-A | MOLDING MATERIALS | TORAY INDUSTRIES (JP) | 1989-11-07 | — | — | US | disclosed |
| EP-0292251-A2 | Aromatic polyester composition and process for producing the same | TORAY INDUSTRIES, INC. (JP) | 1988-11-23 | — | — | EP | disclosed |