Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510512 | 0.91 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9579660 | 0.89 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9579691 | 0.87 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9579697 | 0.85 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9508043 | 0.81 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9579712 | 0.80 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9507999 | 0.79 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9579693 | 0.77 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9506812 | 0.77 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1ALOX5MEN1LMNA | |
| SCHEMBL9508078 | 0.77 | GRM2 (0.52) | CYSLTR2CYSLTR1ALOX5MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5191108-A | Lipoxygenase inhibitors, antiinflammatory agents | HOFFMANN-LA ROCHE INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5025036-A | Antiinflammatory agents, gastrointestinal, cardiovascular and skin disorders | HOFFMANN-LA ROCHE INC. (US) | 1991-06-18 | — | — | US | disclosed |