Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 1/20 | 0.53 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.53 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | VDR | P11473 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16225843 | 0.89 | CYP2D6 (0.63) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL2155391 | 0.89 | CYP2D6 (0.63) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL16227067 | 0.89 | CYP2D6 (0.63) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL16906787 | 0.88 | OSBP (0.53) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL9580113 | 0.86 | GPBAR1 (0.51) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL22572509 | 0.85 | GPBAR1 (0.62) | GPBAR1CASP7HSD17B10TDP1TP53 | |
| SCHEMBL23359045 | 0.85 | ST6GAL1 (0.51) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL6064363 | 0.85 | GPBAR1 (0.61) | GPBAR1CASP7HSD17B10TDP1TP53 | |
| SCHEMBL6651462 | 0.85 | ST6GAL1 (0.51) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 | |
| SCHEMBL22495528 | 0.85 | GPBAR1 (0.56) | OSBPOSBP2ST6GAL1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562849-A2 | Steroid derivatives | ELI LILLY AND COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0562849-A2 | Steroid derivatives | ELI LILLY AND COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |