Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 7/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | CLK2 | P49760 | 1/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034122 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9582852 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9582727 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9582976 | 0.99 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9583159 | 0.99 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9034760 | 0.99 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9582082 | 0.99 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| Hydrochloric Acid SCHEMBL9583449 | 0.99 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9582000 | 0.95 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9034517 | 0.95 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185337-A | Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |