Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 6/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.34 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9583497 | 0.90 | TLR2 (0.34) | TLR2TBXAS1ALDH1A1LMNA | |
| SCHEMBL9583922 | 0.90 | TLR2 (0.34) | TLR2TBXAS1ALDH1A1LMNA | |
| SCHEMBL9583266 | 0.88 | TLR2 (0.34) | TLR2TBXAS1 | |
| SCHEMBL9584577 | 0.88 | HPGD (0.38) | HPGDFLT4KDRTP53 | |
| SCHEMBL9583030 | 0.85 | TLR2 (0.33) | TLR2TBXAS1 | |
| SCHEMBL9584017 | 0.84 | CCNE2 (0.37) | TLR2TBXAS1 | |
| SCHEMBL9584085 | 0.84 | TLR2 (0.34) | TLR2TBXAS1 | |
| SCHEMBL9584124 | 0.83 | TLR2 (0.34) | TLR2TBXAS1ALDH1A1LMNA | |
| SCHEMBL9583392 | 0.82 | HPGD (0.42) | HPGDFLT4KDRTP53ALDH1A1 | |
| SCHEMBL9584499 | 0.81 | CYP1A2 (0.46) | EP300ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250535-A | Herpes virus; nontoxic; side effect reduction; humans and veterinary medicine | SYNTEX INC. (US) | 1993-10-05 | — | — | US | disclosed |
| US-4803271-A | Process for preparing guanine derivatives | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4612314-A | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0085424-A2 | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl)purines as antiviral agent | SYNTEX (U.S.A.) INC. (US) | 1983-08-10 | — | — | EP | disclosed |