Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8442586 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL8441571 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL8443793 | 1.00 | PRSS1 (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL7753353 | 0.98 | TSHR (0.50) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL82662 | 0.85 | CYP3A4 (0.66) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL27008512 | 0.84 | PRSS1 (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL26633470 | 0.84 | PRSS1 (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL2990536 | 0.84 | PRSS1 (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL29042199 | 0.84 | PRSS1 (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 | |
| SCHEMBL29240282 | 0.84 | PRSS1 (0.53) | PRSS1PRSS2PRSS3TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254695-A | Water immiscible solutoins for solvent extraction of metals | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |
| US-4879388-A | AQUEOUS SOLUTIONS CONTAINING HALIDES | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1989-11-07 | — | — | US | disclosed |