Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | DBH | P09172 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9584277 | 0.73 | POLB (0.54) | POLBKMT2AATMDBHALDH1A1 | |
| SCHEMBL9585681 | 0.73 | POLB (0.50) | POLBKMT2AATMDBHALDH1A1 | |
| SCHEMBL9585202 | 0.72 | POLB (0.49) | POLBKMT2AATMDBHALDH1A1 | |
| SCHEMBL9583743 | 0.70 | POLB (0.47) | POLBKMT2AATMDBH | |
| Hydrochloric Acid SCHEMBL17361360 | 0.68 | — | — | |
| SCHEMBL11565100 | 0.67 | — | — | |
| SCHEMBL9584015 | 0.67 | POLB (0.54) | POLBKMT2AATMDBHALDH1A1 | |
| SCHEMBL26129787 | 0.66 | — | — | |
| SCHEMBL9442374 | 0.66 | POLB (0.53) | POLBKMT2AATMDBHALDH1A1 | |
| SCHEMBL9594134 | 0.66 | POLB (0.53) | POLBKMT2AATMDBHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189052-A | Hypotensive agent | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-02-23 | — | — | US | disclosed |
| US-5057613-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS (US) | 1991-10-15 | — | — | US | disclosed |
| US-4810800-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-03-07 | — | — | US | disclosed |