Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586526 | 0.99 | MEN1 (0.46) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL9585121 | 0.92 | MEN1 (0.45) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL9586821 | 0.91 | MEN1 (0.44) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL9586532 | 0.91 | HTT (0.41) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL9586499 | 0.90 | MEN1 (0.43) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL7430189 | 0.89 | CYP1A2 (0.50) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL9586829 | 0.85 | MEN1 (0.44) | MEN1KMT2AHTTNPSR1ALDH1A1 | |
| SCHEMBL7427956 | 0.82 | MME (0.51) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7430576 | 0.80 | CYP1A2 (0.49) | MEN1KMT2AALDH1A1TP53LMNA | |
| Hydrochloric Acid SCHEMBL7440587 | 0.78 | KMT2A (0.44) | MEN1KMT2AHTTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | claimed |
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |