⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433176 | 0.67 | — | — | |
| SCHEMBL4930689 | 0.56 | — | — | |
| SCHEMBL13679653 | 0.54 | — | — | |
| SCHEMBL707812 | 0.54 | — | — | |
| SCHEMBL19743847 | 0.54 | — | — | |
| SCHEMBL701713 | 0.52 | — | — | |
| SCHEMBL17104869 | 0.51 | — | — | |
| SCHEMBL1520907 | 0.50 | — | — | |
| Hydrogen Peroxide SCHEMBL28986039 | 0.50 | — | — | |
| SCHEMBL158318 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373809-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | Novartis AG (CH) | 2024-05-29 | — | — | EP | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | claimed |
| EP-2694509-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN-RELATED KINASES | PFIZER LTD (GB) | 2016-05-18 | — | — | EP | claimed |
| US-20140364415-A1 | PYRROLO[2,3-d]PYRIMIDINE TROPOMYSIN-RELATED KINASE INHIBITORS | PFIZER LIMITED (GB) | 2014-12-11 | — | — | US | claimed |
| US-8846698-B2 | Pyrrolo[2,3-d]pyrimidine tropomysin-related kinase inhibitors | PFIZER LIMITED (US) | 2014-09-30 | — | — | US | claimed |
| EP-2694509-A1 | PYRROLO [2, 3 -D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN- RELATED KINASES | Pfizer Limited (GB) | 2014-02-12 | — | — | EP | claimed |
| US-20130072470-A1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC. (US) | 2013-03-21 | — | — | US | claimed |
| US-20120258950-A1 | PYRROLO[2,3-d]PYRIMIDINE TROPOMYSIN-RELATED KINASE INHIBITORS | PFIZER LIMITED (GB) | 2012-10-11 | — | — | US | claimed |
| WO-2012137089-A1 | PYRROLO [2, 3 -D] PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN- RELATED KINASES | PFIZER LIMITED (GB) | 2012-10-11 | — | — | WO | claimed |
| EP-0560055-B1 | Immuno-suppressing enepyranose derivatives | ISHIHARA SANGYO KAISHA (JP) | 2002-08-28 | — | — | EP | claimed |
| EP-0465913-B1 | Diaminotrifluoromethylpyrimidine derivatives, process for their production and phospholipase A2 inhibitor containing them | ISHIHARA SANGYO KAISHA (JP) | 1997-09-10 | — | — | EP | claimed |
| US-5492908-A | ANTIARTHRITIC | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-02-20 | — | — | US | claimed |
| US-5348967-A | Diaminotrifluoromethylpyridine derivatives, process for their production and phospholipase A2 inhibitor containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1994-09-20 | — | — | US | claimed |
| EP-0465913-A2 | Diaminotrifluoromethylpyrimidine derivatives, process for their production and phospholipase A2 inhibitor containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-01-15 | — | — | EP | claimed |
| JP-1071873-A | — | — | None | — | — | JP | disclosed |
| EP-4373809-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | Novartis AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| EP-0465913-A2 | Diaminotrifluoromethylpyrimidine derivatives, process for their production and phospholipase A2 inhibitor containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| WO-1989002890-A1 | THIOHYDANTOIN COMPOUNDS | OGAWA, KAZUO | 1989-04-06 | — | — | WO | disclosed |
| JP-S6471873-A | RHODANINE COMPOUND | TAIHO PHARMACEUTICAL CO LTD | 1989-03-16 | — | — | JP | disclosed |