Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9587928 | 0.90 | CYP3A4 (0.53) | KDM4ECHRM1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9587878 | 0.88 | CYP3A4 (0.66) | KDM4ECYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9587576 | 0.87 | MEN1 (0.57) | CYP3A4CYP2D6CYP2C9CYP2C19HSD11B1 | |
| SCHEMBL9588899 | 0.86 | HSD17B10 (0.58) | KDM4ECHRM1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9589632 | 0.86 | HSD17B10 (0.58) | KDM4ECHRM1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9598169 | 0.86 | HTT (0.64) | KDM4ECYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9587661 | 0.85 | NPC1 (0.54) | KDM4ECYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9588605 | 0.84 | CHRM1 (0.59) | KDM4ECHRM1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9587211 | 0.84 | CYP3A4 (0.49) | KDM4ECHRM1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7298078 | 0.82 | KDM4E (0.59) | KDM4ECHRM1CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190974-A | Analgesics | ROUSSEL UCLAF (FR) | 1993-03-02 | — | — | US | disclosed |