SCHEMBL9587207

SCHEMBL9587207

CCCCCCCc1cnc(C(=O)O)c(-c2ccccc2)c1OCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.42
RARB P10826 4/20 0.41
PPARA Q07869 2/20 0.41
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
PPARG P37231 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40
TP53 P04637 1/20 0.40
TSHR P16473 1/20 0.40
PTPN11 Q06124 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9588303 1.00 CNR2 (0.42) CNR2RARBPPARABIDMCL1
SCHEMBL9588943 0.85 PTPN11 (0.46) CNR2RARBTP53TSHRPTPN11
SCHEMBL7550301 0.78 PTPN11 (0.46) CNR2RARBTSHRPTPN11
SCHEMBL29067606 0.71 CNR2 (0.46) CNR2RARBPPARGTP53TSHR
SCHEMBL29067603 0.71 CNR2 (0.46) CNR2RARBPPARGTP53TSHR
SCHEMBL27402471 0.71 TDP1 (0.46) CNR2TP53TSHRPTPN11
SCHEMBL11868801 0.70 BID (0.54) PPARABIDMCL1BCL2L1BAK1
SCHEMBL7078027 0.70 BID (0.54) PPARABIDMCL1BCL2L1BAK1
SCHEMBL10592243 0.70 BID (0.54) PPARABIDMCL1BCL2L1BAK1
SCHEMBL5453797 0.70 BID (0.54) PPARABIDMCL1BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0220296-B1 SMECTIC LIQUID CRYSTALLINE PHASES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-28 EP disclosed
EP-0220296-A1 SMECTIC LIQUID CRYSTALLINE PHASES. MERCK PATENT GMBH (DE) 1987-05-06 EP disclosed
WO-1986006401-A1 SMECTIC LIQUID CRYSTALLINE PHASES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-11-06 WO disclosed