Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.76 |
| ▸ | MAOA | P21397 | 4/20 | 0.76 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.73 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 2/20 | 0.59 |
| ▸ | RXRB | P28702 | 2/20 | 0.59 |
| ▸ | RXRG | P48443 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411878 | 0.90 | MRGPRX4 (0.77) | MAOBMAOANR4A2MRGPRX4 | |
| SCHEMBL8694329 | 0.86 | MAOB (1.00) | MAOBMAOANR4A2NPC1CYP1A2 | |
| SCHEMBL2654709 | 0.86 | MRGPRX4 (0.71) | MAOBMAOANR4A2MRGPRX4 | |
| SCHEMBL1122805 | 0.86 | MRGPRX4 (0.71) | MAOBNR4A2MRGPRX4 | |
| SCHEMBL30412034 | 0.86 | MAOB (0.73) | MAOBNR4A2MRGPRX4 | |
| SCHEMBL976424 | 0.86 | MAOB (0.73) | MAOBNR4A2MRGPRX4 | |
| SCHEMBL30412015 | 0.85 | MRGPRX4 (0.63) | MAOBMAOANR4A2MRGPRX4NPC1 | |
| SCHEMBL975973 | 0.85 | MRGPRX4 (0.63) | MAOBMAOANR4A2MRGPRX4NPC1 | |
| SCHEMBL8231874 | 0.85 | MAOB (0.75) | MAOBMAOANR4A2MRGPRX4 | |
| SCHEMBL10659025 | 0.85 | MRGPRX4 (0.74) | MAOBMAOAMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204482-A | Ethylenediamine monoamide heteroaryl derivatives | HOFFMAN-LAROCHE INC. (US) | 1993-04-20 | — | — | US | disclosed |
| US-5011849-A | Monoamine oxidase inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1991-04-30 | — | — | US | disclosed |