SCHEMBL958878

SCHEMBL958878

NCCOCCN.O=C(O)CN(CCOCCN(CC(=O)O)CC(=O)OCCO)CC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BLM P54132 2/20 0.56
PMP22 Q01453 2/20 0.56
HSD17B10 Q99714 1/20 0.56
CA1 P00915 17/20 0.49
CA2 P00918 17/20 0.49
CA4 P22748 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
ADRA2A P08913 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
CYP2C19 P33261 1/20 0.41
ADRA1A P35348 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6690950 0.92 BLM (0.66) BLMPMP22HSD17B10CA1CA2
Ethylene Glycol SCHEMBL2860610 0.87 BLM (0.68) BLMPMP22HSD17B10CA1CA2
Ethylene Glycol SCHEMBL1742779 0.87 BLM (0.68) BLMPMP22HSD17B10CA1CA2
SCHEMBL9156858 0.85 KDM4E (0.47) BLMPMP22HSD17B10CA1CA2
SCHEMBL15508717 0.85 BLM (0.69) BLMPMP22HSD17B10CA1CA2
SCHEMBL2770982 0.85 BLM (0.76) BLMPMP22HSD17B10CA1CA2
SCHEMBL5852343 0.84 TDP1 (0.60) BLMPMP22HSD17B10CA1CA2
SCHEMBL3831965 0.84 BLM (0.80) BLMPMP22HSD17B10CA1CA2
SCHEMBL5850288 0.84 TDP1 (0.60) BLMPMP22HSD17B10CA1CA2
Hydrochloric Acid SCHEMBL15516229 0.84 BLM (0.67) BLMPMP22HSD17B10CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130071834-A1 COMPOSITIONS AND METHODS USEFUL FOR HCV INFECTION VERTEX PHARMACEUTICALS INCORPORATED (US) 2013-03-21 US claimed
US-7871783-B2 Method for activating an antigen, method for detecting a cell, and solution for activating an antigen SYSMEX CORPORATION (JP) 2011-01-18 US claimed
EP-1975615-B1 Method for detecting a cell as well as use of an agent for breaking a hydrogen bond SYSMEX CORP (JP) 2009-10-28 EP claimed
EP-1975615-A1 Method for activating an antigen, method for detecting a cell, use of an agent for breaking a hydrogen bond, solution for activating an antigen Sysmex Corporation (JP) 2008-10-01 EP claimed
US-20080160542-A1 METHOD FOR ACTIVATING AN ANTIGEN, METHOD FOR DETECTING A CELL, AND SOLUTION FOR ACTIVATING AN ANTIGEN SYSMEX CORPORATION (JP) 2008-07-03 US claimed
EP-0891554-B1 METHOD OF MEASURING BILIRUBIN BECKMAN COULTER INC (US) 2003-06-18 EP claimed
US-5783407-A Method of measuring bilirubin BECKMAN INSTRUMENTS, INC. (US) 1998-07-21 US claimed
US-5700653-A THIOL COMPOUND, FREE RADICAL SCAVENGER STABILIZER, MAGNESIUM COMPOUND, AND LIQUID BECKMAN INSTRUMENTS, INC. (US) 1997-12-23 US claimed
US-11639924-B2 Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier FUJIFILM CORPORATION (JP) 2023-05-02 US disclosed
US-20200393449-A1 TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-12-17 US disclosed
US-10794899-B2 Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-10-06 US disclosed
EP-3690041-A1 TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER FUJIFILM Wako Pure Chemical Corporation (JP) 2020-08-05 EP disclosed
EP-3228709-B1 TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2020-05-20 EP disclosed
US-20180120299-A1 TIM PROTEIN-BOUND CARRIER, METHODS FOR OBTAINING, REMOVING AND DETECTING EXTRACELLULAR MEMBRANE VESICLES AND VIRUSES USING SAID CARRIER, AND KIT INCLUDING SAID CARRIER WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2018-05-03 US disclosed
US-20020142449-A1 Compositions and methods useful for HCV infection VERTEX PHARMACEUTICALS INCORPORATED 2002-10-03 US disclosed
US-20020086342-A1 Assays for identifying phosphatase inhibitors SCHAEFFER ERIC (US) 2002-07-04 US disclosed
EP-1001977-A2 RADIOLABELED PEPTIDES FOR THE DIAGNOSIS AND TREATMENT OF BREAST AND PROSTATE TUMORS AND METASTASES OF SUCH TUMORS MALLINCKRODT INC. (US) 2000-05-24 EP disclosed
WO-1999062563-A2 RADIOLABELED PEPTIDES FOR THE DIAGNOSIS AND TREATMENT OF BREAST AND PROSTATE TUMORS AND METASTASES OF SUCH TUMORS MALLINCKRODT INC. (US) 1999-12-09 WO disclosed
US-5863746-A A TEST KIT FOR DETECTING IN A TEST SAMPLE, AN ANALYTE THAT UNDERGOES AUTO-OXIDATION, CONTAINS AQUEOUS MEDIUM, FREE RADICAL SCAVENGER AND ENZYMES WHICH CATALYZE OXIDATION BECKMAN COULTER, INC. (US) 1999-01-26 US disclosed
US-5783407-A Method of measuring bilirubin BECKMAN INSTRUMENTS, INC. (US) 1998-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080160542-A1 METHOD FOR ACTIVATING AN ANTIGEN, METHOD FOR DETECTING A CELL, AND SOLUTION FOR ACTIVATING AN ANTIGEN CD69, NFATC1, CD74 BLM 4279/4885PMP22 2567/4885HSD17B10 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.