Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 9/20 | 0.59 |
| ▸ | FNTA | P49354 | 4/20 | 0.59 |
| ▸ | FNTB | P49356 | 4/20 | 0.59 |
| ▸ | SLC6A15 | Q9H2J7 | 10/20 | 0.54 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592263 | 0.94 | PTAFR (0.60) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9592313 | 0.90 | PTAFR (0.55) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9591515 | 0.88 | PTAFR (0.60) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL8876671 | 0.88 | PTAFR (0.64) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9590656 | 0.87 | PTAFR (0.62) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9593377 | 0.87 | FNTA (0.65) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9589545 | 0.85 | PTAFR (0.56) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9592566 | 0.83 | PTAFR (0.74) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9663718 | 0.83 | PTAFR (0.57) | PTAFRFNTAFNTBSLC6A15HRH1 | |
| SCHEMBL9591552 | 0.82 | SLC6A15 (0.75) | PTAFRFNTAFNTBSLC6A15HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231101-A | Antihistamines | SS PHARMACEUTICAL CO., LTD. (JP) | 1993-07-27 | — | — | US | disclosed |
| EP-0495484-A1 | Novel benzo [5,6] cyclohepta [1,2-b] pyridine derivatives and antiallergic agents comprising same | SS PHARMACEUTICAL CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |