Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345269 | 1.00 | HRH3 (0.46) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9592135 | 1.00 | HRH3 (0.46) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9345279 | 1.00 | HRH3 (0.46) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9345144 | 0.96 | HRH3 (0.49) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9590568 | 0.96 | HRH3 (0.49) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9590576 | 0.96 | HRH3 (0.49) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9345132 | 0.96 | HRH3 (0.49) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9591103 | 0.94 | HRH3 (0.46) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9591112 | 0.94 | HRH3 (0.46) | HRH3ITGB3ITGA2BKCNH2MEN1 | |
| SCHEMBL9346807 | 0.94 | HRH3 (0.46) | HRH3ITGB3ITGA2BKCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238600-A | IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |