Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL27730181 | 0.96 | MAPT (0.57) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL1176227 | 0.88 | MAPT (0.50) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL6113793 | 0.87 | MAPT (0.56) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL5929615 | 0.84 | KDM4E (0.58) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL31005978 | 0.84 | KDM4E (0.58) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL15521004 | 0.83 | MAPT (0.52) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL2472386 | 0.83 | CSNK2A1 (0.60) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL18932044 | 0.82 | MAPT (0.55) | MAPTHPGDCDK2ALDH1A1POLB | |
| SCHEMBL5945664 | 0.82 | CSNK2A1 (0.64) | MAPTHPGDCDK2POLBMEN1 | |
| SCHEMBL6152964 | 0.82 | MAPT (0.57) | MAPTHPGDCDK2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | ASTEX TECHNOLOGY, INC. (GB) | 2006-06-22 | — | — | US | claimed |
| JP-2006500348-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1534685-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | Astex Technology Limited (GB) | 2005-06-01 | — | — | EP | claimed |
| WO-2004014864-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | ASTEX TECHNOLOGY LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
| US-20250339569-A1 | CARBONIC ANHYDRASE IX LIGANDS | 3B PHARMACEUTICALS GMBH (DE) | 2025-11-06 | — | — | US | disclosed |
| CN-118561776-A | N- (3-fluorobenzyl) -1H-indazole-5-amine derivative and application thereof | 沈阳药科大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-114605329-B | Substituted indazole carboxamides or substituted azaindazole carboxamides FLT3 inhibitors and uses thereof | 河南中医药大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114605329-A | Substituted indazole carboxamide or substituted azaindazole carboxamide FLT3 inhibitors and uses thereof | 河南中医药大学 | 2022-06-10 | — | — | CN | disclosed |
| US-9249125-B2 | Pyrazole derivatives as p38 MAP inhibitors | RESPIVERT LIMITED (GB) | 2016-02-02 | — | — | US | disclosed |
| US-9249125-B2 | Pyrazole derivatives as p38 MAP inhibitors | RESPIVERT LIMITED (GB) | 2016-02-02 | — | — | US | disclosed |
| US-9249125-B2 | Pyrazole derivatives as p38 MAP inhibitors | RESPIVERT LIMITED (GB) | 2016-02-02 | — | — | US | disclosed |
| US-20150203475-A1 | PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS | TOPIVERT PHARMA LIMITED (GB) | 2015-07-23 | — | — | US | disclosed |
| US-5124231-A | Mixture of hydrazine derivative, redox compound, and melting point lowering agent | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-23 | — | — | US | disclosed |
| US-5085971-A | Redox system capable of releasing development inhibitor by oxidation and a hydrazine compound | FUJI PHOTO FILM CO., LTD. (JP) | 1992-02-04 | — | — | US | disclosed |
| EP-0442323-A2 | Silver halide color reversal photographic material capable of providing interimage effect | FUJI PHOTO FILM CO., LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0436027-A1 | METHOD OF TREATING SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-5006444-A | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0420005-A1 | high contrast silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0398285-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |
| EP-0395069-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150203475-A1 | PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS | SYK, FYN, MAPK1 | MAPT 1617/4885HPGD 1794/4885CDK2 538/4885 |
| US-20250339569-A1 | CARBONIC ANHYDRASE IX LIGANDS | CA9, CA13, CA4 | MAPT 2838/4885HPGD 3198/4885CDK2 3820/4885 |
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | CCNC, CDK1, CDK7 | MAPT 4723/4885HPGD 1261/4885CDK2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.