Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688608 | 0.90 | HTT (0.53) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| Hydrochloric Acid SCHEMBL11764056 | 0.88 | HTT (0.52) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL830927 | 0.81 | HTT (0.46) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL7131764 | 0.79 | HTT (0.45) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL30434815 | 0.79 | HTT (0.55) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL11587838 | 0.78 | HTT (0.39) | HTTALDH1A1TSHRMAPTATM | |
| SCHEMBL8508636 | 0.78 | HTT (0.44) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL1220936 | 0.78 | HTT (0.50) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL10489058 | 0.78 | HTT (0.50) | HTTALDH1A1TSHRTAAR1KCNN4 | |
| SCHEMBL9788880 | 0.77 | HTT (0.53) | HTTALDH1A1TSHRTAAR1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451753-A1 | In the ethylenic moiety substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkyl-ethylenediamines | ASTA Medica Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | claimed |
| US-5238955-A | Anticarcinogenic agents | ASTA PHARMA AG (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5238955-A | Anticarcinogenic agents | ASTA PHARMA AG (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5194644-A | Antitumor agents; treatment of leukemia | ASTA PHARMA AG (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0451753-A1 | In the ethylenic moiety substituted phenylalkylethylenediamine-platinum (II or IV) derivatives and phenylalkyl-ethylenediamines | ASTA Medica Aktiengesellschaft (DE) | 1991-10-16 | — | — | EP | disclosed |