Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596622 | 0.93 | DPP8 (0.40) | DPP8DPP9ABCB1TGM2BMP1 | |
| SCHEMBL9519366 | 0.85 | DPP8 (0.42) | DPP8DPP9ABCB1TGM2BMP1 | |
| SCHEMBL7859716 | 0.85 | PSEN1 (0.39) | DPP8DPP9ALDH1A1MAPTHPGD | |
| SCHEMBL9596597 | 0.85 | ABCB1 (0.42) | DPP8DPP9ABCB1TGM2BMP1 | |
| SCHEMBL9136917 | 0.85 | DPP8 (0.39) | DPP8DPP9ABCB1TGM2CYP19A1 | |
| SCHEMBL7859861 | 0.84 | PSEN1 (0.40) | DPP8DPP9ALDH1A1MAPTHPGD | |
| SCHEMBL8113715 | 0.83 | DPP8 (0.41) | DPP8DPP9ABCB1TGM2BMP1 | |
| SCHEMBL9595730 | 0.83 | DPP8 (0.43) | DPP8DPP9ABCB1TGM2BMP1 | |
| SCHEMBL8106599 | 0.82 | DPP8 (0.42) | DPP8DPP9TGM2BMP1ALDH1A1 | |
| SCHEMBL9137731 | 0.82 | HTT (0.39) | ALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |