Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722471 | 0.81 | CYP1A2 (0.47) | CYP1A2 | |
| SCHEMBL29226117 | 0.75 | — | — | |
| SCHEMBL27989796 | 0.72 | POLB (0.31) | POLB | |
| SCHEMBL4155992 | 0.72 | HCAR2 (0.41) | — | |
| SCHEMBL4155990 | 0.72 | HCAR2 (0.41) | — | |
| SCHEMBL491500 | 0.71 | MEN1 (0.31) | — | |
| SCHEMBL4807624 | 0.71 | TSHR (0.34) | — | |
| SCHEMBL11946886 | 0.70 | POLB (0.32) | POLB | |
| SCHEMBL16583787 | 0.70 | MEN1 (0.35) | — | |
| SCHEMBL21141616 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194442-A | 2,3,4,5-tetrahydro-1-benzoxepins, the use thereof and pharmaceutical products based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0360131-A1 | 2,3,4,5-Tetrahydro-1-benzoxepines, method for their preparation, their use and pharmaceutical compositions based on these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-28 | — | — | EP | disclosed |