Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107979 | 1.00 | NR1H2 (0.36) | NR1H2MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8106571 | 0.92 | NR1H2 (0.35) | NR1H2MEN1KMT2A | |
| SCHEMBL8112404 | 0.92 | NR1H2 (0.35) | NR1H2MEN1KMT2A | |
| SCHEMBL9595653 | 0.92 | NR1H2 (0.35) | NR1H2MEN1KMT2A | |
| Water SCHEMBL8098440 | 0.91 | NR1H2 (0.34) | NR1H2MEN1KMT2A | |
| SCHEMBL8108016 | 0.88 | NR1H2 (0.32) | NR1H2MEN1KMT2A | |
| SCHEMBL8098400 | 0.87 | NR1H2 (0.32) | NR1H2 | |
| SCHEMBL9595228 | 0.87 | NR1H2 (0.32) | NR1H2 | |
| SCHEMBL8106756 | 0.86 | NR1H2 (0.31) | NR1H2 | |
| SCHEMBL8106777 | 0.86 | NR1H2 (0.31) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |