Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847354 | 0.78 | GAA (0.38) | PPM1BPTPN1PPP1CCGAAALDH1A1 | |
| SCHEMBL3838195 | 0.78 | KMT2A (0.46) | GAAALDH1A1ALOX15THRBATM | |
| SCHEMBL3843370 | 0.78 | KMT2A (0.50) | GAAALDH1A1ALOX15THRBATM | |
| SCHEMBL13480843 | 0.76 | CHRM2 (0.50) | SMN1; SMN2 | |
| SCHEMBL7055895 | 0.74 | CHRM1 (0.41) | — | |
| SCHEMBL18618479 | 0.70 | CHRM1 (0.38) | GAAALDH1A1MAPTALOX15THRB | |
| SCHEMBL18589689 | 0.70 | KMT2A (0.41) | PPM1BPTPN1PPP1CCGAAALDH1A1 | |
| SCHEMBL3139522 | 0.70 | CHRM1 (0.50) | GAA | |
| SCHEMBL29822414 | 0.69 | CHRM1 (0.49) | GAAALDH1A1ALOX15THRBATM | |
| SCHEMBL13321596 | 0.68 | CHRM1 (0.55) | GAAALDH1A1THRBATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179090-A | Antiischemic agents; treatment of asthma, bronchitis, heart diseases | DR. KARL THOMAE GMBH (DE) | 1993-01-12 | — | — | US | disclosed |
| EP-0417630-A2 | Condensed diazepinones, process for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1991-03-20 | — | — | EP | disclosed |