Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9596605 | 1.00 | GRIN2B (0.55) | GRIN2BKMT2AKDM4ETHRBGRIN1 | |
| SCHEMBL4863537 | 0.79 | KMT2A (0.55) | KMT2AKDM4ETHRBRAB9AGAA | |
| SCHEMBL9214547 | 0.78 | KDM4E (0.51) | KMT2AKDM4ETHRBRAB9AGAA | |
| SCHEMBL9216403 | 0.78 | KDM4E (0.51) | KMT2AKDM4ETHRBRAB9AGAA | |
| SCHEMBL9597052 | 0.76 | MAPT (0.61) | KMT2ARAB9AHTTCYP11B1CYP11B2 | |
| SCHEMBL7295106 | 0.76 | KMT2A (0.51) | KMT2AKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL22281477 | 0.76 | CYP3A4 (0.54) | KMT2AKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL5056593 | 0.76 | CYP3A4 (0.54) | KMT2AKDM4ERAB9ACYP1A2CYP3A4 | |
| SCHEMBL4093147 | 0.76 | GRIN2B (0.65) | GRIN2BGRIN1CYP3A4CYP2C19 | |
| SCHEMBL1232170 | 0.76 | GRIN2B (0.70) | GRIN2BGRIN1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5272164-A | Carboximidamide derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-12-21 | — | — | US | disclosed |