Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199339 | 0.91 | FSCN1 (0.55) | LMNAFSCN1ADORA3ADORA2AKDM4E | |
| SCHEMBL17038827 | 0.89 | FSCN1 (0.69) | LMNAFSCN1ADORA3ADORA2AKDM4E | |
| SCHEMBL30501120 | 0.89 | FSCN1 (0.69) | LMNAFSCN1ADORA3ADORA2AKDM4E | |
| SCHEMBL959580 | 0.86 | CPT1A (0.55) | LMNAFSCN1ADORA3ADORA2AKDM4E | |
| SCHEMBL959604 | 0.83 | FSCN1 (0.62) | FSCN1ADORA3ADORA2APTGER4 | |
| SCHEMBL958894 | 0.79 | CPT1A (0.48) | LMNAFSCN1ADORA3ADORA2AKDM4E | |
| SCHEMBL958517 | 0.79 | PTGER4 (0.59) | LMNAFSCN1ADORA3ADORA2ASMN1; SMN2 | |
| SCHEMBL958250 | 0.78 | FSCN1 (0.54) | LMNAFSCN1ADORA3KDM4EMAPK1 | |
| SCHEMBL958253 | 0.78 | P2RY14 (0.58) | FSCN1ADORA3ADORA2AL3MBTL1PTGER4 | |
| SCHEMBL17038832 | 0.77 | FSCN1 (0.59) | LMNAFSCN1ADORA3ADORA2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015234-A1 | INDAZOLE DERIVATIVES | ACKERMANN JEAN | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015234-A1 | INDAZOLE DERIVATIVES | CPT1A, CPT1B, CES1 | LMNA 2675/4885FSCN1 4651/4885ADORA3 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.