Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234726 | 0.93 | HRH3 (0.46) | HRH3DRD2DRD3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8229020 | 0.93 | HRH3 (0.51) | HRH3DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9656222 | 0.92 | HRH3 (0.49) | HRH3 | |
| SCHEMBL8234535 | 0.92 | HRH3 (0.49) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL8237539 | 0.92 | HRH3 (0.49) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL9656112 | 0.90 | HRH3 (0.48) | HRH3ALDH1A1TP53TSHRMAPK1 | |
| SCHEMBL9598438 | 0.90 | CACNA1B (0.43) | HRH3ALDH1A1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL9598319 | 0.89 | HRH3 (0.47) | HRH3BCHEACHE | |
| Oxalic Acid SCHEMBL9599573 | 0.89 | HRH3 (0.43) | HRH3ALDH1A1SMN1; SMN2BCHEACHE | |
| SCHEMBL4171578 | 0.88 | HRH3 (0.37) | HRH3ALDH1A1TP53TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182291-A | Angina pectoris, hypotensive, antiarrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5039700-A | Cardiovascular disorders, antitumor agents | SANOFI (FR) | 1991-08-13 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4957925-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA | SANOFI (FR) | 1990-09-18 | — | — | US | disclosed |