Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 9/20 | 0.59 |
| ▸ | SMARCA4 | P51532 | 8/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565023 | 0.89 | POLB (0.64) | SMARCA2SMARCA4POLBANO1AR | |
| SCHEMBL10558595 | 0.86 | SMARCA2 (0.57) | SMARCA2SMARCA4POLBANO1AR | |
| SCHEMBL9598470 | 0.85 | SMARCA2 (0.66) | SMARCA2SMARCA4ANO1KMT2AAR | |
| SCHEMBL9599834 | 0.80 | SMARCA2 (0.86) | SMARCA2SMARCA4KMT2ANPC1ALDH1A1 | |
| SCHEMBL3322673 | 0.80 | SMARCA2 (0.66) | SMARCA2SMARCA4ANO1KMT2AAR | |
| SCHEMBL10502486 | 0.77 | SMARCA2 (0.62) | SMARCA2SMARCA4KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL22125117 | 0.77 | SMARCA2 (0.67) | SMARCA2SMARCA4KMT2AARRAB9A | |
| SCHEMBL2616482 | 0.76 | SMARCA2 (0.60) | SMARCA2SMARCA4ARKDM4EALDH1A1 | |
| SCHEMBL10561825 | 0.76 | SMARCA2 (0.61) | SMARCA2SMARCA4POLBARPIK3CA | |
| SCHEMBL10561427 | 0.75 | SMARCA2 (0.59) | SMARCA2SMARCA4ANO1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243450-B1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC Corporation (US) | 1993-04-28 | — | — | EP | claimed |
| EP-0243450-A4 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1989-09-11 | — | — | EP | claimed |
| US-4818271-A | PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1989-04-04 | — | — | US | claimed |
| EP-0243450-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1987-11-04 | — | — | EP | claimed |
| WO-1987002665-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC CORPORATION (US) | 1987-05-07 | — | — | WO | claimed |