Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 3/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865363 | 0.82 | HSP90AA1 (0.41) | NPC1RAB9AHSP90AA1TLR7HSP90AB1 | |
| SCHEMBL1131137 | 0.78 | HSP90AA1 (0.44) | TSHRNPC1RAB9AHSP90AA1PIK3CA | |
| SCHEMBL12393233 | 0.77 | TSHR (0.35) | TSHRTLR7NUDT1 | |
| SCHEMBL29340871 | 0.77 | CDK1 (0.46) | TSHRTLR8 | |
| SCHEMBL25659408 | 0.76 | TSHR (0.41) | TSHRTLR7TLR8NUDT1 | |
| SCHEMBL30562916 | 0.74 | HSP90AB1 (0.43) | TSHRNPC1RAB9AHSP90AA1PIK3CA | |
| SCHEMBL441545 | 0.74 | HSP90AB1 (0.43) | TSHRNPC1RAB9AHSP90AA1PIK3CA | |
| Fluoride SCHEMBL31379739 | 0.73 | HSP90AB1 (0.41) | TSHRNPC1RAB9AHSP90AA1PIK3CA | |
| SCHEMBL24728017 | 0.72 | MAPT (0.41) | NPC1RAB9AHSP90AA1HSP90AB1 | |
| SCHEMBL21364208 | 0.72 | TLR7 (0.40) | TSHRTLR7NUDT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010086-A1 | PROCESS FOR PREPARING N-(ARYLSULPHONYL)-CARBAMIDE ACID DERIVATES AND INTERMEDIATES USEFUL FOR CARRYING OUT THIS PROCESS | MTA Központi Kémiai Kutató Intézete (HU) | 1993-05-27 | — | — | WO | disclosed |