Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.45 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9598423 | 0.97 | HRH3 (0.48) | HRH3BCHEACHE | |
| Oxalic Acid SCHEMBL9599094 | 0.94 | HRH3 (0.48) | HRH3BCHEACHE | |
| Oxalic Acid SCHEMBL10337873 | 0.93 | HRH3 (0.50) | HRH3BCHEACHE | |
| Hydrochloric Acid SCHEMBL9656561 | 0.89 | HRH3 (0.48) | HRH3BCHEACHE | |
| SCHEMBL9599491 | 0.88 | HRH3 (0.54) | HRH3 | |
| Hydrochloric Acid SCHEMBL9600032 | 0.87 | HRH3 (0.53) | HRH3 | |
| Oxalic Acid SCHEMBL9598414 | 0.86 | MEN1 (0.43) | HRH3 | |
| Oxalic Acid SCHEMBL9598449 | 0.86 | HRH3 (0.49) | HRH3BCHE | |
| Hydrochloric Acid SCHEMBL9598375 | 0.86 | HRH3 (0.53) | HRH3 | |
| Oxalic Acid SCHEMBL9599573 | 0.86 | HRH3 (0.43) | HRH3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182291-A | Angina pectoris, hypotensive, antiarrhythmia, cerebral vascular insufficiency | SANOFI (FR) | 1993-01-26 | — | — | US | disclosed |
| US-5147878-A | Hypotensive, antiarrhythmia agents | SANOFI (FR) | 1992-09-15 | — | — | US | disclosed |
| US-5039700-A | Cardiovascular disorders, antitumor agents | SANOFI (FR) | 1991-08-13 | — | — | US | disclosed |
| US-5017579-A | Use of aminoalkoxyphenyl derivatives for reducing and/or controlling excessive intraocular pressure | SANOFI (FR) | 1991-05-21 | — | — | US | disclosed |
| US-4957925-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS, TREATMENT OF ANGINA | SANOFI (FR) | 1990-09-18 | — | — | US | disclosed |