Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 7/20 | 0.59 |
| ▸ | SMARCA4 | P51532 | 6/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502486 | 0.92 | SMARCA2 (0.62) | SMARCA2SMARCA4EPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL3322673 | 0.85 | SMARCA2 (0.66) | SMARCA2SMARCA4 | |
| SCHEMBL9600748 | 0.84 | SMARCA2 (0.63) | SMARCA2SMARCA4HTTALDH1A1 | |
| SCHEMBL9599834 | 0.80 | SMARCA2 (0.86) | SMARCA2SMARCA4EPHX1EPHX2HTT | |
| SCHEMBL11310806 | 0.79 | NAMPT (0.65) | EPHX1HTTSMN1; SMN2ATMALDH1A1 | |
| SCHEMBL10560427 | 0.79 | SMARCA2 (0.61) | SMARCA2SMARCA4 | |
| SCHEMBL13296457 | 0.78 | EPHX2 (0.71) | EPHX1EPHX2HTTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11310061 | 0.78 | NAMPT (0.64) | EPHX1HTTSMN1; SMN2ATMALDH1A1 | |
| SCHEMBL22125520 | 0.77 | SMARCA2 (0.76) | SMARCA2SMARCA4EPHX1EPHX2 | |
| SCHEMBL22125117 | 0.77 | SMARCA2 (0.67) | SMARCA2SMARCA4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243450-B1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC Corporation (US) | 1993-04-28 | — | — | EP | claimed |
| EP-0243450-A4 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1989-09-11 | — | — | EP | claimed |
| US-4818271-A | PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1989-04-04 | — | — | US | claimed |
| EP-0243450-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1987-11-04 | — | — | EP | claimed |
| WO-1987002665-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC CORPORATION (US) | 1987-05-07 | — | — | WO | claimed |