Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.56 |
| ▸ | PGR | P06401 | 4/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110494 | 0.94 | NR1I2 (0.56) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL9602336 | 0.93 | NR1I2 (0.48) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL9659884 | 0.92 | NR1I2 (0.65) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL9600756 | 0.92 | NR1I2 (0.47) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL11004980 | 0.91 | NR1I2 (0.57) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL11107647 | 0.91 | NR1I2 (0.56) | NR1I2PGRPTGS2TDP1APEX1 | |
| Hydrochloric Acid SCHEMBL10746059 | 0.91 | NR1I2 (0.56) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL10744052 | 0.91 | NR1I2 (0.56) | NR1I2PGRPTGS2TDP1APEX1 | |
| Hydrochloric Acid SCHEMBL10740147 | 0.91 | NR1I2 (0.56) | NR1I2PGRPTGS2TDP1APEX1 | |
| SCHEMBL10745848 | 0.91 | NR1I2 (0.56) | NR1I2PGRPTGS2TDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| EP-0188254-A2 | Cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |