Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049487 | 0.88 | KDM4E (0.53) | JMJD6ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL17518844 | 0.84 | JMJD6 (0.77) | JMJD6LMNAALDH1A1ESR1CHRM1 | |
| SCHEMBL25049489 | 0.84 | KDM4C (0.57) | ALDH1A1TSHRKDM4EMAPTACACB | |
| SCHEMBL8406007 | 0.83 | JMJD6 (0.59) | JMJD6LMNAALDH1A1ESR1CHRM1 | |
| SCHEMBL4090687 | 0.82 | JMJD6 (0.51) | JMJD6ESR1 | |
| SCHEMBL27953095 | 0.81 | JMJD6 (0.58) | JMJD6LMNAALDH1A1ESR1CHRM1 | |
| SCHEMBL28765609 | 0.81 | JMJD6 (0.58) | JMJD6LMNAALDH1A1ESR1CHRM1 | |
| SCHEMBL3723629 | 0.81 | JMJD6 (0.56) | JMJD6LMNAESR1CYP1A2CYP3A4 | |
| SCHEMBL4087566 | 0.81 | JMJD6 (0.50) | JMJD6LMNAESR1CYP1A2CYP3A4 | |
| SCHEMBL17412497 | 0.79 | KDM4E (0.54) | JMJD6LMNAALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0243450-B1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC Corporation (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0243450-A4 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1989-09-11 | — | — | EP | disclosed |
| US-4818271-A | PLANT GROWTH REGULATORS | FMC CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |
| EP-0243450-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES. | FMC CORP (US) | 1987-11-04 | — | — | EP | disclosed |
| WO-1987002665-A1 | PYRIDINYLUREA COMPOUNDS AND AGRICULTURAL USES | FMC CORPORATION (US) | 1987-05-07 | — | — | WO | disclosed |