Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732002 | 0.86 | ATM (0.50) | ATMMAPTCASP1ALDH1A1CYP2C19 | |
| SCHEMBL11686027 | 0.80 | ATM (0.42) | ATMMAPTCASP1ALDH1A1CYP3A4 | |
| SCHEMBL21606739 | 0.80 | ATM (0.48) | ATMALDH1A1CYP2C19 | |
| SCHEMBL1200736 | 0.80 | ATM (0.62) | ATMMAPT | |
| SCHEMBL1200775 | 0.80 | ATM (0.62) | ATMMAPT | |
| SCHEMBL1200738 | 0.80 | ATM (0.62) | ATMMAPT | |
| SCHEMBL3255533 | 0.78 | ATM (0.77) | ATMCASP1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL1362502 | 0.78 | ATM (0.77) | ATMCASP1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7719287 | 0.78 | ATM (0.77) | ATMCASP1ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL434233 | 0.78 | ATM (0.77) | ATMCASP1ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |