Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264228 | 1.00 | KMT2A (0.43) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9262394 | 0.89 | KMT2A (0.44) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9262397 | 0.89 | KMT2A (0.44) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9259011 | 0.88 | KMT2A (0.42) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9258999 | 0.88 | KMT2A (0.42) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9263786 | 0.87 | KMT2A (0.43) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9263781 | 0.87 | KMT2A (0.43) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9265611 | 0.87 | KMT2A (0.44) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9265614 | 0.87 | KMT2A (0.44) | KMT2AATML3MBTL1POLBEPHX1 | |
| SCHEMBL9381098 | 0.86 | KMT2A (0.42) | KMT2AATML3MBTL1POLBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993010087-A1 | DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION | G.D. SEARLE & CO. (US) | 1993-05-27 | — | — | WO | disclosed |