Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TKT | P29401 | 11/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179151 | 0.83 | KDM4E (0.39) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL859044 | 0.83 | — | — | |
| SCHEMBL18995146 | 0.83 | KDM4E (0.35) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL9602691 | 0.81 | — | — | |
| SCHEMBL9069716 | 0.80 | KDM4E (0.60) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL13059262 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL10985285 | 0.79 | KDM4E (0.38) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL742334 | 0.75 | KDM4E (0.35) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL26937705 | 0.75 | — | — | |
| SCHEMBL18381552 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1020340-C | 1-carbacephalosporin antibiotics | LILLY CO ELI (US) | 1993-04-21 | — | — | CN | disclosed |
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |
| CN-86108961-A | 1-CARBACEPHALOSPORIN ANTIBIOTICS | — | 1987-08-05 | — | — | CN | disclosed |