Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614715 | 0.83 | HRH1 (0.50) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL8614712 | 0.83 | HRH1 (0.50) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL11609902 | 0.70 | HTR2B (0.52) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL4999007 | 0.70 | HTR2B (0.55) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL4173949 | 0.70 | HTR2B (0.55) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL4999010 | 0.70 | HTR2B (0.55) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL4173944 | 0.70 | HTR2B (0.55) | HRH1ALDH1A1KCNH2HTR2BLMNA | |
| SCHEMBL8143124 | 0.69 | TBXA2R (0.53) | TBXA2R | |
| SCHEMBL8143121 | 0.69 | TBXA2R (0.53) | TBXA2R | |
| SCHEMBL8506363 | 0.69 | HRH1 (0.62) | HRH1ALDH1A1KCNH2HTR2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5339223-A | — | — | None | — | — | JP | disclosed |
| JP-H05339223-A | TRICYCLIC COMPOUND | KYOWA HAKKO KOGYO CO LTD | 1993-12-21 | — | — | JP | disclosed |