Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601592 | 1.00 | CTDSP1 (0.56) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9602756 | 0.91 | NR1I2 (0.49) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9602765 | 0.91 | NR1I2 (0.49) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9601903 | 0.91 | NR1I2 (0.49) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9601915 | 0.91 | NR1I2 (0.49) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9600724 | 0.89 | NR1I2 (0.48) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9600718 | 0.89 | NR1I2 (0.48) | CTDSP1TDP1MAPTL3MBTL1POLB | |
| SCHEMBL9602244 | 0.88 | NR1I2 (0.66) | CTDSP1TDP1MAPTPOLBALDH1A1 | |
| SCHEMBL9602255 | 0.88 | NR1I2 (0.66) | CTDSP1TDP1MAPTPOLBALDH1A1 | |
| SCHEMBL11459698 | 0.88 | CTDSP1 (0.61) | CTDSP1TDP1MAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| EP-0188254-A2 | Cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |