Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.49 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.49 |
| ▸ | NT5E | P21589 | 2/20 | 0.49 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.40 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14429248 | 0.93 | POLB (0.65) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14429203 | 0.93 | POLB (0.65) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14429237 | 0.93 | POLB (0.65) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL23211670 | 0.91 | POLB (0.86) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL23211669 | 0.91 | POLB (0.86) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL5180666 | 0.88 | POLB (0.67) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL2582769 | 0.86 | POLB (0.52) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL14429302 | 0.85 | POLB (0.56) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL14429301 | 0.85 | POLB (0.56) | POLBABL1RIN1P2RY6P2RY14 | |
| SCHEMBL2577572 | 0.84 | POLB (0.55) | POLBABL1RIN1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355135-B1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4997926-A | Viricides | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0355135-A1 | ADENOSINE DEAMINASE-STABLE ANTI-RETROVIRAL NUCLEOSIDES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-02-28 | — | — | EP | disclosed |