Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13595077 | 0.82 | HSD17B10 (0.50) | HSD17B10HDAC8KCNH2ACHETSHR | |
| SCHEMBL13595082 | 0.80 | KCNH2 (0.50) | HSD17B10HDAC8KCNH2 | |
| SCHEMBL1551957 | 0.80 | HSD17B10 (0.49) | HSD17B10HDAC8KCNH2ACHETSHR | |
| Fluoride Ion SCHEMBL30331061 | 0.78 | HSD17B10 (0.47) | HSD17B10HDAC8KCNH2ACHETSHR | |
| SCHEMBL18824248 | 0.78 | HSD17B10 (0.47) | HSD17B10HDAC8KCNH2ACHETSHR | |
| SCHEMBL30569303 | 0.78 | HSD17B10 (0.47) | HSD17B10HDAC8KCNH2ACHETSHR | |
| Iodide SCHEMBL4408127 | 0.78 | KCNH2 (0.48) | HSD17B10HDAC8KCNH2SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL11431543 | 0.78 | HSD17B10 (0.47) | HSD17B10HDAC8KCNH2ACHETSHR | |
| SCHEMBL9602287 | 0.78 | HSD17B10 (0.47) | HSD17B10HDAC8KCNH2ACHETSHR | |
| SCHEMBL20273198 | 0.78 | HSD17B10 (0.44) | HSD17B10HDAC8KCNH2ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |