Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13055389 | 0.90 | TAAR1 (0.60) | TAAR1NPC1RAB9AGAAHSD17B10 | |
| SCHEMBL18389610 | 0.86 | — | — | |
| SCHEMBL9276339 | 0.86 | TAAR1 (0.57) | TAAR1NPC1RAB9AGAA | |
| SCHEMBL989310 | 0.85 | — | — | |
| SCHEMBL21891729 | 0.85 | — | — | |
| SCHEMBL2243907 | 0.85 | SMN1; SMN2 (0.63) | TAAR1NPC1RAB9AGAAHSD17B10 | |
| SCHEMBL7786363 | 0.85 | — | — | |
| SCHEMBL8944700 | 0.83 | TAAR1 (0.54) | TAAR1NPC1RAB9AGAAHSD17B10 | |
| SCHEMBL1416061 | 0.83 | HSD17B10 (0.55) | TAAR1NPC1RAB9AGAAHSD17B10 | |
| SCHEMBL1895210 | 0.83 | TAAR1 (0.58) | TAAR1NPC1RAB9AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |