⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL964399 | 0.77 | — | — | |
| SCHEMBL11671905 | 0.74 | — | — | |
| SCHEMBL2566427 | 0.71 | — | — | |
| SCHEMBL2802830 | 0.69 | — | — | |
| SCHEMBL960023 | 0.67 | — | — | |
| SCHEMBL7927573 | 0.67 | — | — | |
| SCHEMBL7923861 | 0.65 | — | — | |
| SCHEMBL2801680 | 0.65 | — | — | |
| SCHEMBL2566432 | 0.64 | — | — | |
| SCHEMBL2567600 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149549-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |
| WO-2023149548-A1 | NOVEL PHARMACEUTICAL COMPOSITION | 国立大学法人富山大学 | 2023-08-10 | — | — | WO | disclosed |
| US-9611258-B2 | Dual MEK/PI3K inhibitors and therapeutic methods using the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-04-04 | — | — | US | disclosed |
| CN-105358156-A | Dual MEK/PI3K inhibitors and therapeutic methods using the same | UNIV MICHIGAN | 2016-02-24 | — | — | CN | disclosed |
| EP-2968345-A1 | DUAL MEK/PI3K INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | The Regents of The University of Michigan (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20160002212-A1 | DUAL MEK/PI3K INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2016-01-07 | — | — | US | disclosed |
| CN-102977440-B | Polyolefin resin composition | ADEKA CORP | 2015-04-01 | — | — | CN | disclosed |
| CN-102977439-B | Polyolefin resin composition | ADEKA CORP | 2015-03-25 | — | — | CN | disclosed |
| WO-2014171894-A1 | SYNTHESIS OF CYCLIC CARBONATES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-23 | — | — | WO | disclosed |
| WO-2014164942-A1 | DUAL MEK/PI3K INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-10-09 | — | — | WO | disclosed |
| CN-1294581-A | Pyridine derivative and pharmaceutical contg. same | OTSUKA PHARMA CO LTD (JP) | 2001-05-09 | — | — | CN | disclosed |
| EP-1066261-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| US-6022998-A | ELECTRON CHARGE TRANSFERRING MATERIAL (PARTICULARLY HOLE TRANSFERRING MATERIAL) IN AN ELECTROPHOTOSENSITIVE MATERIAL | MITA INDUSTRIAL CO., LTD. (JP) | 2000-02-08 | — | — | US | disclosed |
| WO-1999048871-A1 | PYRIDINE DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-30 | — | — | WO | disclosed |
| CN-1030768-C | Primidine derivatives, process for preparing same and inhibitor for androgen | OTSUKA PHARMA CO LTD (JP) | 1996-01-24 | — | — | CN | disclosed |
| US-5420128-A | Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0503099-A1 | PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |
| CN-1060844-A | Pyrimidine derivatives, its method for making and inhibitor for androgen | OTSUKA PHARMA CO LTD (JP) | 1992-05-06 | — | — | CN | disclosed |
| CN-85108908-A | Polymerizing catalyst and its preparation and application | — | 1986-08-06 | — | — | CN | disclosed |
| US-4016160-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-04-05 | — | — | US | disclosed |