Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8516388 | 0.84 | KDM4E (0.58) | KDM4EEPHX2KDM4CGRIN1GRIN2A | |
| SCHEMBL8515153 | 0.84 | KDM4E (0.58) | KDM4EEPHX2KDM4CGRIN1GRIN2A | |
| SCHEMBL13403402 | 0.84 | EPHX2 (0.63) | KDM4EEPHX2HDAC1HDAC6GABRP | |
| SCHEMBL8513622 | 0.82 | KDM4E (0.58) | KDM4EEPHX2KDM4CGRIN1GRIN2A | |
| SCHEMBL10730956 | 0.80 | EPHX2 (0.59) | KDM4EEPHX2HDAC1HDAC6GABRP | |
| SCHEMBL24976247 | 0.80 | EPHX2 (0.53) | KDM4EEPHX2HDAC1HDAC6GABRP | |
| SCHEMBL7326932 | 0.79 | GRIN1 (0.60) | KDM4EGRIN1GRIN2AGRIN2BHDAC1 | |
| SCHEMBL29127177 | 0.78 | EPHX2 (0.63) | KDM4EEPHX2KDM4CHDAC1HDAC6 | |
| SCHEMBL23913095 | 0.77 | HDAC6 (0.63) | HDAC1HDAC6 | |
| SCHEMBL2614261 | 0.77 | GRIN1 (0.58) | KDM4EGRIN1GRIN2AGRIN2BHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069608-A1 | TECHNETIUM-99M COMPLEX AS A TOOL FOR THE IN VIVO DIAGNOSIS OF CANCEROUS TUMOURS | PIERRE FABRE MEDICAMENT (FR) | 2012-05-31 | — | — | WO | disclosed |