Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777140 | 0.89 | CYP1A2 (0.50) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8776881 | 0.89 | CYP1A2 (0.50) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8776938 | 0.89 | PDE10A (0.51) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8776659 | 0.87 | CYP1A2 (0.46) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8776930 | 0.87 | CYP1A2 (0.48) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8776954 | 0.87 | CYP1A2 (0.48) | CYP1A2NPC1MAPTSMN1; SMN2PDE10A | |
| SCHEMBL8777229 | 0.87 | CYP1A2 (0.48) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9607587 | 0.86 | CYP1A2 (0.45) | CYP1A2MEN1KMT2ANPC1ATM | |
| SCHEMBL8777323 | 0.86 | NPC1 (0.46) | CYP1A2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3788033 | 0.85 | CYP1A2 (0.46) | CYP1A2NPC1PDE10AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |