Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779470 | 0.83 | BRD4 (0.39) | BRD4KMT2AMEN1NPC1PDE5A | |
| SCHEMBL8779392 | 0.83 | PDE10A (0.46) | BRD4KMT2AMEN1NPC1PDE5A | |
| SCHEMBL8779457 | 0.81 | SMN1; SMN2 (0.41) | BRD4KMT2AMEN1NPC1PDE5A | |
| SCHEMBL3787489 | 0.80 | MAPT (0.50) | KMT2AMEN1PDE5AL3MBTL1ALDH1A1 | |
| SCHEMBL8779492 | 0.79 | KDM4E (0.41) | BRD4KMT2AMEN1NPC1PDE5A | |
| SCHEMBL8779414 | 0.78 | MEN1 (0.54) | BRD4KMT2AMEN1PDE5AL3MBTL1 | |
| SCHEMBL8779486 | 0.78 | PDE5A (0.36) | BRD4KMT2AMEN1NPC1PDE5A | |
| SCHEMBL8779415 | 0.78 | MAPT (0.53) | BRD4KMT2AMEN1PDE5AL3MBTL1 | |
| SCHEMBL8779388 | 0.77 | PDE5A (0.45) | KMT2AMEN1NPC1PDE5AL3MBTL1 | |
| SCHEMBL8779369 | 0.77 | MEN1 (0.53) | KMT2AMEN1METAP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069652-A2 | FUNGICIDE MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |
| WO-2010136475-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-12-02 | — | — | WO | disclosed |