SCHEMBL9607773

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9607774	0.79	PIK3CA (0.46)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL1114284	0.79	HDAC1 (0.52)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL799559	0.79	HDAC1 (0.41)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL799551	0.78	MTOR (0.51)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL14960380	0.78	MTOR (0.55)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL1114005	0.78	MTOR (0.51)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL799437	0.78	MTOR (0.51)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL1114167	0.78	HDAC1 (0.56)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL799510	0.77	MTOR (0.52)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1
	SCHEMBL799240	0.76	HDAC1 (0.46)	PIK3CAPIK3CDPIK3CGHDAC1PIK3R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.